logo

Surface bioactivity of plasma implanted silicon and amorphous carbon

LOW ENERGY ACCELERATOR, RAY TECHNOLOGY AND APPLICATIONS

Surface bioactivity of plasma implanted silicon and amorphous carbon

Paul K CHU
Nuclear Science and TechniquesVol.15, No.3pp.144-154Published in print 01 Jun 2004
26001

Plasma immersion ion implantation and deposition (PIII&D) has been shown to be an effective technique to enhance the surface bioactivity of materials. In this paper, recent progress made in our laboratory on plasma surface modification single-crystal silicon and amorphous carbon is reviewed. Silicon is the most important material in the integrated circuit industry but its surface biocompatibility has not been investigated in details. We have recently performed hydrogen PIII into silicon and observed the biomimetic growth of apatite on its surface in simulated body fluid. Diamond-like carbon (DLC) is widely used in the industry due to its excellent mechanical properties and chemical inertness. The use of this material in biomedical engineering has also attracted much attention. It has been observed in our laboratory that doping DLC with nitrogen by means of PIII can improve the surface blood compatibility. The properties as well as in vitro biological test results will be discussed in this article.

Hydrogen implanted siliconPlasmaBioactivityApatiteDiamond-like carbonAmorphous carbonBlood compatibility
References
[1] Hench L L, Anderson O. Bioactive glass in An introduction to bioceramics (Hench L L, Wilson J eds), World Scientific, USA, 1993, 41-62
[2] De Aza P N, Guitian F, De Aza S. Sript Metal, 1994, 31: 1001-1005
[3] Liu X, Ding C. J Biomed Mater Res, 2002, 59(2): 259-264
[4] Liu X, Ding C. Biomater, 2001, 22(14): 2007-2012
[5] Cho S, Nakanishi K, Kokubo T et al. J Am Ceram Soc, 1995, 78: 1769-1774
[6] Canham L T, Reeves C L. Proc MRS, Boston, MA, 1996, 189-194
[7] Karlsson K H, Fröberg K, Ringbom T. J Non-Cryst Solids, 1989, 112: 69-72
[8] Carlisle E M.

Silicon as an essential trace element in animal nutrition

, in silicon biochemistry (Everd D, O'Connor M et al. eds), John Wiley & Sons, Chichester · New York · Sydney · Toronto · Singapore, 1986, 123-139
Baidu ScholarGoogle Scholar
[9] Hidebrand M, Higgins D R, Busser K et al. Gene, 1993, 132: 213
[10] Hench L L. Thermochimica Acta, 1996, 280(281): 1-13
[11] Keeting P E, Wiegand K E, Spelssberg T C et al. American Soc Bone and Mineral Res, Annual Meeting, Atlanta, GA. USA, Abst. #184
[12] Xynos I D, Hukkanen M V J, Batten J J et al. Calcif Tiss Int, 2000, 67: 321-329
[13] Xynos I D, Edgar A J, Buttery L D et al. Biochem Biophys Res Comm, 2000, 276: 461-465
[14] Corbett J W, Deak P, Desnica U V et al. Hydrogen passivation of damage centers in semiconductors in hydrogen in semiconductors (Pankove J I, Johnson N M eds), Academic Press, San Diego, 1991, 49-64
[15] Tong Q Y, Gösele U M. Adv Mater, 1999, 11(17): 1409-1425
[16] Piatkowska A, Gawlik G, Jagielski J. Appl Surf Sci, 1999, 141: 333-338
[17] Grisolia J, Cristiano F, Assayag G B et al. Nucl Instr and Meth B, 2001, 178: 160-164
[18] Reboredo F A, Ferconi M, Pantelides S T. Phys Rev Lett, 1999, 82(24): 4870-4873
[19] Zhang S B, Jackson W B. Phys Rev B, 1991, 43(14): 12142-12145
[20] Iwata H, Takagi M, Tokuda Y et al. J Cryst Growth, 2000, 210: 94-97
[21] Dahmen C, Janotta A, Dimova-Malinovska D et al. Thin Solid Films, 2003, 427: 201-207
[22] Liu X Y, Fu R K Y, Poon R W Y et al.

Biomimetic growth of apatite on hydrogen implanted silicon

, Biomater (in press, 2004)
Baidu ScholarGoogle Scholar
[23] Wang X H, Zhang F, Li C R et al. Surf Coat Tech, 2000, 128-129: 36-42
[24] Cui F Z, Li D J. Surf Coat Technol, 2000, 131: 481-487
[25] Grill A. Diamond Relat Mater, 2003, 12(2): 166-170
[26] Rodil S E, Olivares R, Arzate H et al. Diamond Relat Mater, 2003, 12(3-7): 931-937
[27] Chen J Y, Wang L P, Fu K Y et al. Surf Coat Technol, 2002, 156: 289-294
[28] Yang P, Kwok S C H, Chu P K et al. Nucl Instrum Meth Phys Res B, 2003, 206: 721-725
[29] Leng Y X, Chen J Y, Yang P et al. Surf Sci, 2003, 531: 177-184
[30] Sheeja D, Tay BK, Nung L N. Diamond Relat Mater, 2004, 13-1:184-190
[31] Hauert R. Diamond Relat Mater, 2003, 12(3-7): 583-589
[32] Inaba H, Fujimaki S, Sasaki S et al. Jpn J Appl Phys, 2002, 41: 5730-5733
[33] Chang Y Y, Wang D Y, Wu W T. Diamond Relat Mater, 2003, 12(10-11): 2077-2082
[34] Zhang X W, Ke N, Cheung W Y et al. Diamond Relat Mater, 2003, 12(1): 1-77
[35] Tessier P Y, Pichon L, Villechaise P et al. Diamond Relat Mater, 2003, 12(3-7): 1066-1069
[36] Chu P K, Chen J Y, Wang L P et al. Mater Sci Engin Report, 2002, 36: 143-206
[37] Kwok S C H, Yang P, Wang J et al.

Haemocompatibility of nitrogen-doped, hydrogen-free diamond-like carbon prepared by plasma immersion ion implantation - deposition

, J Biomed Mater Res (in press, 2004)
Baidu ScholarGoogle Scholar
[38] Chu P K, Qin S, Chan C et al.

Mater Sci Engin Reports

, 1996, 17: 207-280
Baidu ScholarGoogle Scholar
[39] Chu P K, Tang B Y, Cheng Y C et al. Rev Sci Instrum, 1997, 68: 1866-1874
[40] Fan Z N, Zeng X C, Kwok D T K et al. IEEE Trans Plasma Sci, 2000, 28: 371-375
[41] Kokubo T, Kushitani H, Sakka S et al. J Biomed Mater Res, 1990, 24: 721-734
[42] Weng J, Liu Q, Wolke J G C et al. Biomater, 1997, 18: 1027-1035
[43] Chu P K, Tang B Y, Wang L P et al. Rev Sci Instrum, 2001, 72(3): 1660-1665
[44] Chen J Y, Leng Y X, Tian X B et al. Biomater, 2002, 23(12): 2545-2552
[45] Lifshitz Y. Diamond Relat Mater, 1999, 8: 1659-1676
[46] Cheng Y H, Tay B K, Lau S P et al. Diamond Relat Mater, 2001, 10(12): 2107-2278
[47] Ferrari A C, Rodil S, Robertson J. Diamond Relat Mater, 2003, 12(3-7): 905-910
[48] Yang P, Huang N, Leng Y X et al. Biomater, 2003, 24: 2821-2829
[49] Zhou Z M, Xia L F. J Phys D: Appl Phys, 2002, 35: 1991-1996
[50] Dementjev A P, Graaf A D, van de Sanden M C M et al. Diamond Relat Mater, 2000, 9(11): 1904-1907
[51] Petrov P, Dimitrov D B, Krastev V et al. Diamond Relat Mater, 2000, 9(3-6): 562-565
[52] Merel P, Tabbal M, Chaker M et al. Appl Surf Sci, 1998, 136: 105-110
[53] Zhou Z M, Xia L F. J Phys D: Appl Phys, 2002, 35: 1991-1996
[54] Goodman S L. J Biomed Mater Res, 1999, 45(3): 240-250
[55] Zhang X W, Ke N, Cheung W Y et al. Diamond Relat Mater, 2003, 12: 1-7
[56] Yang P, Huang N, Leng Y X et al. Chin J Biomed Engin, 2002, 21(1): 90-93