Clinical value of 18F-FDG PET/CT in evaluation of hepatic vein, inferior vena cava and right atrium tumor thrombi in hepatocellular carcinoma: Initial results

RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE

Clinical value of ¹⁸F-FDG PET/CT in evaluation of hepatic vein, inferior vena cava and right atrium tumor thrombi in hepatocellular carcinoma: Initial results

SUN Long，

ZHAO Long，

LUO Zuoming，

JIANG Maoqing，

WU Hua

Nuclear Science and Techniques

Vol.23, No.3

pp.169-175

Published in print 20 Jun 2012

DOI：10.13538/j.1001-8042/nst.23.169-175

31800

In this paper, eleven consecutive hepatocellular carcinoma (HCC) patients with an embolus in the hepatic vein (HV), inferior vena cava (IVC)and right atrium (RA) were studied with ¹⁸F-FDG PET/CT and contrast enhanced CT. When correlated with final diagnosis, ¹⁸F-FDG PET/CT and contrast enhanced CT was positive in 11 patients (100%), 7 patients (63.6%), respectively. The accuracy of PET/CT and contrast-enhanced CT were 100%, 63.6%. Three cases with secondary blood thrombi in the distant IVC, which were confirmed by PET/CT, cannot be identified by contrast enhanced CT. The average survival was 3 months (range, 1-12mo). The 12 months survival rate was 9.1%. Our results suggest that highly metabolic tumor thrombus in the HV, IVC and RA may be depicted on ¹⁸F-FDG PET/CT in HCC patients. It may discriminate between malignant and secondary benign blood thrombi.

Hepatocellular carcinomaContrast-enhanced CTPositron emission tomography/computed tomographyHepatic vein tumor thrombusRight atriumTumor thrombus

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