Proportion of viable myocardium is more reliable than semi-quantitative score in predicting functional recovery: a pilot study of PET myocardial viability imaging
RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE|Updated:2021-01-29
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Proportion of viable myocardium is more reliable than semi-quantitative score in predicting functional recovery: a pilot study of PET myocardial viability imaging
Nuclear Science and TechniquesVol. 19, Issue 1, (2008)
Affiliations:
1.Department of Nuclear Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
2.Department of Cardiac / Thoracic Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
Jiayin ZHANG, Ye KONG, Jian ZHOU, et al. Proportion of viable myocardium is more reliable than semi-quantitative score in predicting functional recovery: a pilot study of PET myocardial viability imaging. [J]. Nuclear Science and Techniques 19(1):32-38(2008)
DOI:
Jiayin ZHANG, Ye KONG, Jian ZHOU, et al. Proportion of viable myocardium is more reliable than semi-quantitative score in predicting functional recovery: a pilot study of PET myocardial viability imaging. [J]. Nuclear Science and Techniques 19(1):32-38(2008) DOI: 10.1016/S1001-8042(08)60018-4.
Proportion of viable myocardium is more reliable than semi-quantitative score in predicting functional recovery: a pilot study of PET myocardial viability imaging
PET myocardial viability imaging is the "gold standard" for the non-invasive assessment of myocardial viability. The research aims to find out the best methods of imaging interpretation in predicting the postoperative functional recovery. Twenty-one CAD patients with multi-vessel involvement were recruited. All patients underwent gated myocardial perfusion imaging(G-MPI) and FDG PET myocardial imaging within 2 weeks before coronary artery bypass grafting. The postoperative G-MPI was performed in all patients 3 months after the surgery. Out of the total 420 segments, 164 segments of ischemic myocardium were detected by preoperative G-MPI. Among them, 93 ischemic segments were identified as non-viable(difference score≥0) and the rest 71 segments were identified as viable(difference score<0). The proportion of viable segments (the ratio of viable segments versus ischemic segments) and summed difference score of metabolism to perfusion were calculated. The patients were further divided into 2 groups according to the proportion of viable myocardium: groupⅠ(the proportion≥50%, 12 cases) and groupⅡ(the proportion<50%, 9 cases) while another division was made according to SDS: group A (SDS≥0), group B (-5≤SDS<0) and group C (SDS<-5). The diagnostic accuracy of proportion of viable segments and SDS in predicting the post-revascularization improvement in the left ventricular ejection fraction by at least 5 or more ejection fraction units was 88.89% (8/9) and 55.56% (5/9) respectively. It is concluded that both approaches allow accurate evaluation of myocardial viability. Furthermore, the proportion of viable myocardium is more reliable in predicting the postoperative functional recovery.
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