Zeliang SHI, Shuhui ZHOU, Shen FU. Potential applications of synchrotron radiation to the treatment of cancer. [J]. Nuclear Science and Techniques 24(1):010101(2013)
DOI:
Zeliang SHI, Shuhui ZHOU, Shen FU. Potential applications of synchrotron radiation to the treatment of cancer. [J]. Nuclear Science and Techniques 24(1):010101(2013) DOI: 10.13538/j.1001-8042/nst.2013.01.006.
Potential applications of synchrotron radiation to the treatment of cancer
Although conventional radiotherapy remains to be one of the most useful treatments for cancer, it is not the best strategy to maximize the effects on the tumors and minimize the damage to the surrounding tissues due to its physical and biological characteristics. Synchrotron radiation (SR) with uniquely physical and biological advantages may represent an innovative approach for cancer treatment. In recent years, SR-based photon activation therapy, stereotactic synchrotron radiation therapy and micro-beam radiation treatment have been developed, and the results of ,in vitro, and ,in vivo, experiments are very promising. It is necessary to understand the physical and radiobiological principle of those novel strategies before the approach is applied to the clinic. In this paper, we summarize the advances of SR in terms of physical, radiobiological advantages and its potential clinical applications. With the successful operation of shanghai synchrotron radiation, good opportunities in China have been provided for investigations on the treatment of cancer with synchrotron radiation.