An analytical simulation technique for cone-beam CT and pinhole SPECT

An analytical simulation technique for cone-beam CT and pinhole SPECT 1 first-author 1 corresp Corresponding author. E-mail address: qiyujin@sinap.ac.cn Corresponding author. E-mail address: qiyujin@sinap.ac.cn qiyujin@sinap.ac.cn Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China This study was aimed at developing an efficient simulation technique with an ordinary PC. The work involved derivation of mathematical operators, analytic phantom generations, and effective analytical projectors developing for cone-beam CT and pinhole SPECT imaging. The computer simulations based on the analytical projectors were developed by ray-tracing method for cone-beam CT and voxel-driven method for pinhole SPECT of degrading blurring. The 3D Shepp–Logan, Jaszczak and Defrise phantoms were used for simulation evaluations and image reconstructions. The reconstructed phantom images were of good accuracy with the phantoms. The results showed that the analytical simulation technique is an efficient tool for studying cone-beam CT and pinhole SPECT imaging. Computer simulation Mathematical Phantom Cone-beam CT Pinhole SPECT References Rubinstein R Y . Simulation and the Monte Carlo method , Wiley - New York , 1981 . Simulation and the Monte Carlo method Raeside D E . Monte Carlo principles and applications , Phys Med Biol 1976 , 21 : 181 - 197 . Monte Carlo principles and applications Zaidi H . Med Phys , 1999 , 26 : 574 - 608 . Med Phys Rogers D W O . Phys Med Biol , 2006 , 51 : R287 - R301 . Phys Med Biol Herman G T . Fundamentals of computerized tomography: Image reconstruction from projections ,  Academic Press , 1980 . Fundamentals of computerized tomography: Image reconstruction from projections Kak A C , Slaney M . Principles of computerized tomographic imaging , IEEE Press , 1988 . Principles of computerized tomographic imaging Barrett H H , Mayer K J . Foundations of image science , Wiley-Interscience , 2003 . Foundations of image science Zhang X Z , Chen F F , Qi Y J , et al . Proc IEEE Nucl Sci Symp Conf Rec , 2009 , 3318 - 3321 . Zhang X Z , Qi Y J . Chin Sci Bull , 2011 , 56 : 340 - 348 . Chin Sci Bull Zaidi H , Tsui B M W . Proceedings of the IEEE , 2009 , 97 : 1935 - 1937 . Proceedings of the IEEE Yang M , Lang T , Wei Y . Acta Armamentarii , 2006 , 27 : 437 - 441 . Acta Armamentarii Zhang X Z , Dai Q S , Qi Y J . Proc IEEE Nucl Sci Symp Conf Rec , 2008 , 5255 - 5259 . Feldkmap L A , Davis L C , Kress J W . J Opt Soc Am Al , 1984 , 612 - 619 . J Opt Soc Am Al Hudson H M , Larkin R S . IEEE Trans Med Imaging , 1994 , 13 : 601 - 609 . IEEE Trans Med Imaging 10.13538/j.1001-8042/nst.22.338-343 Supported by National Natural Science Foundation of China (10875162) 2011-08-01 2011-12-20 2021-01-19 2011 Nuclear Science and Techniques 06 22