Joint imaging of 99mTcO4‾ and 99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases

Qingjie MA; Tiefeng JI; Shi GAO; Qiang WEN; Fan WANG; Hui SUN

doi:10.13538/j.1001-8042/nst.21.89-93

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Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases

RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE | 更新时间：2021-01-29

- Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases
- Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases
- 核技术（英文版） 2010年21卷第2期
- 作者机构：
  
  1.China-Japan Union Hospital, Jilin University, Changchun 130033, China
- 作者简介：
  
  Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com
  
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  Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com
  
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- 基金信息：
  
  Nature Science Foundation of Jilin Province
- DOI：10.13538/j.1001-8042/nst.21.89-93 中图分类号：
- 纸质出版日期：2010-04-20，
  
  收稿日期：2009-06-11，
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引用本文
Qingjie MA, Tiefeng JI, Shi GAO, 等. Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases[J]. 核技术（英文版）, 2010, 21(2):89-93.

Qingjie MA, Tiefeng JI, Shi GAO, et al. Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases[J]. Nuclear Science and Techniques, 2010, 21(2):89-93.
Qingjie MA, Tiefeng JI, Shi GAO, 等. Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases[J]. 核技术（英文版）, 2010, 21(2):89-93. DOI： 10.13538/j.1001-8042/nst.21.89-93.

Qingjie MA, Tiefeng JI, Shi GAO, et al. Joint imaging of ^99mTcO₄‾ and ^99mTc-MIBI for thyroid carcinoma recurrence and cervical metastases[J]. Nuclear Science and Techniques, 2010, 21(2):89-93. DOI： 10.13538/j.1001-8042/nst.21.89-93.

Joint imaging of 99m TcO 4 ‾ and 99m Tc-MIBI for thyroid carcinoma recurrence and cervical metastases 1 first-author 1 1 corresp Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com gaoshi800830@163.com 1 1 1 corresp Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com Corresponding author. E-mail address: gaoshi800830@163.com; sunhui1229@163.com gaoshi800830@163.com China-Japan Union Hospital, Jilin University, Changchun 130033, China China-Japan Union Hospital, Jilin University, Changchun 130033, China In this paper, the joint imaging of 99m TcO 4 ‾ and 99m Tc-methoxy isobutyl isonitrile was compared with neck Color Doppler Ultrasonography (CDU) to identify its value in thyroid carcinoma, postoperative recurrence or cervical metastases. Thyroid carcinoma patients (150 operated and 21 re-operated with suspected postoperative recurrence or cervical metastases) were retrospectively analyzed. Taking the pathological result as the gold standard, the thyroid foci (437 cases), the thyroid foci of ≥1-cm diameter (215 cases) and the suspected postoperative recurrence or cervical metastases (87 cases) were compared by diagnostic results of the joint imaging and the neck CDU. The sensitivity, specificity and accuracy of the joint imaging were 64.18%, 80.00% and 67.82%, and 44.78%, 40.00% and 43.68%, respectively, for the cases with suspected postoperative recurrence or cervical metastases. For thyroid carcinoma of ≥1-cm diameter, the sensitivity of the joint imaging was 97.75%, and the neck CDU was 89.89%, but both specificity and accuracy was similar for thyroid carcinoma independence on their diameter. For thyroid carcinoma, the sensitivity of the joint imaging was 81.99%, and the neck CDU was 89.10%. The results show that the joint imaging is sensitive for large diameter thyroid carcinoma. Thyroid carcinoma Radionuclide imaging Tc Methoxy isobutyl isonitrile References Shi B Y . Chin J Endocrinol Metab , 2006 , 22 : 194 - 197 . Chin J Endocrinol Metab Jun J Y , Manni A . Otolaryngol Clin North Am , 2008 , 41 : 1241 - 1260 . Otolaryngol Clin North Am Muller S T , Guth-Tougeides B , Crcuzing H . J Nucl Med , 1987 , 28 : 562 - 564 . J Nucl Med Jin Y M , Fang J C . Suzhou Univ J Med Sci , 2008 , 28 : 831 - 835 . Suzhou Univ J Med Sci Feng J , Li Q S , Li Z Y . J Ultrasound in Clin Med , 2008 , 10 : 676 - 678 . J Ultrasound in Clin Med Shen Y H , Ren Y F , Tang L N , Chin J Med Imaging Tech , 2008 , 16 : 217 - 219 . Chin J Med Imaging Tech Zhang Y X . Nuclear Medicine . Bei Jing : People’s Medical Publishing House , 2005 , 187 - 188 . Nuclear Medicine Ronga G , Ventroni G , Montesano T . J Nucl Med Mol Imaging , 2007 , 51 : 364 - 371 . J Nucl Med Mol Imaging Moretti J L , Hauet N , Caglar M . E J Nucl Med Mol Imaging , 2005 , 32 : 836 - 842 . E J Nucl Med Mol Imaging Sriprapaporn J , Toopmongkol C , Satayaban B . Ann Acad Med , 2002 , 31 : 195 - 19 . Ann Acad Med 10.13538/j.1001-8042/nst.21.89-93 Supported by Nature Science Foundation of Jilin Province (No.200705277) . 2009-06-11 2010-04-20 2021-01-19 2010 Nuclear Science and Techniques 02 21

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