Biological reduction and intracellular trapping differences of ¹⁸⁸Re(VII) and ⁹⁹Tc^m(VII) in Escherichia coli

Biological reduction and intracellular trapping differences of 188 Re(VII) and 99 Tc m (VII) in Escherichia coli 1 2 first-author 1 corresp Corresponding author. E-mail address: yinduanzhi@sinap.ac.cn Corresponding author. E-mail address: yinduanzhi@sinap.ac.cn yinduanzhi@sinap.ac.cn 1 1 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China Graduate School of Chinese Academy of Sciences, Beijing 100049, China Graduate School of Chinese Academy of Sciences, Beijing 100049, China 99 Tc m is the most commonly used diagnostic radioisotope. And 188 Re is an excellent therapeutic radioisotope with a gamma photon for imaging. Both locate in the same group and have very similar properties. 99 Tc m (VII) can be partially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli , and trapped intracellularly. However, 188 Re(VII) cannot be reduced and trapped, because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons. 99 Tc m 188 Re Escherichia coli Biological reduction Intracellular trapping References Garcia-garayoa E , schibli R , schubiger P A . Nucl Sci Technol , 2007 , 18 : 88 - 100 . Nucl Sci Technol Lloyd J R , Macaskie L E . Appl Environ Microbiol , 1996 , 62 : 578 - 582 . Appl Environ Microbiol Lloyd J R , Nolting H F , Sole V A , et al . Geomicrobiol , 1998 , 15 : 43 - 56 . Geomicrobiol Lloyd J R , Cole J A , Macaskie L E . J. Bacteriol , 1997 , 179 : 2014 - 2021 . J. Bacteriol Lloyd J R , Harding C L , Macaskie L E . Biotechnol Bioeng , 1997 , 55 : 505 - 510 . Biotechnol Bioeng Rossmann R , Sawers G , Böck A . Mol Microbiol , 1991 , 5 : 2807 - 2814 . Mol Microbiol Lloyd J R , Thomas G H , Finlay J A . Biotechnol Bioeng , 1999 , 66 : 122 - 130 . Biotechnol Bioeng Bard A J , Parsons R , Jordan J . Standard Potentials in Aqueous Solution . New York (USA) : Marcel Dekker Inc , 1985 , 345 . Standard Potentials in Aqueous Solution Shukla S K . J. Chromatogr , 1966 , 21 : 92 - 111 . J. Chromatogr Breuer M , Schütz A , Engelhardt M , et al . Angiology , 1999 , 50 : 563 - 571 . Angiology Pantuck A J , Berger F , Zisman A , et al . J Urol , 2002 , 168 : 1193 - 1198 . J Urol Peng F Y , Hills B , Li K . Intracellular trapping of radionuclides by enzyme-mediated reduction . US Patent: 2007/0009437 A 1 , 2007-01-11 . Intracellular trapping of radionuclides by enzyme-mediated reduction Karine B , Nelli M , Anna P . FEBS Letters , 2002 , 516 : 172 - 178 . FEBS Letters http://www.ncbi.nlm.nih.gov/ Iznaga-Escobar N . Appl Radiat Isot , 2001 , 54 : 399 - 406 . Appl Radiat Isot Knapp F F . Cancer Biother & Radiopharm , 1998 , 13 : 337 - 341 . Cancer Biother & Radiopharm Yin D Z , Yu J F , Wang Y X . Nucl Technol , 2000 , 23 : 347 - 352 . Nucl Technol Macaskie L E . CRC Crit. Rev. Biotechnol , 1991 , 11 : 41 - 112 . CRC Crit. Rev. Biotechnol Lovley D R . Ann Rev Microbiol , 1993 , 47 : 263 - 290 . Ann Rev Microbiol 10.13538/j.1001-8042/nst.20.27-30 Supported by the Science & Technology Commission of Shanghai Municipality (No. 06DZ19506) , the National Natural Science Foundation of China (No.20501022) and the Project of Knowledge Innovation of Chinese Academy of Sciences (No. KJCXI-SW-08) . 2008-10-21 2009-02-20 2021-01-19 2009 Nuclear Science and Techniques 01 20