E-beam degradation of thiamphenicol and florfenicol

E-beam degradation of thiamphenicol and florfenicol 1 first-author 1 corresp Corresponding author. E-mail address: mhwu@staff.shu.edu.cn Corresponding author. E-mail address: mhwu@staff.shu.edu.cn mhwu@staff.shu.edu.cn 1 1 1 1 Shanghai Applied Radiation Institute, Shanghai University, Shanghai 200444, China Shanghai Applied Radiation Institute, Shanghai University, Shanghai 200444, China Thiamphenicol (THA) and florfenicol (FLO) aqueous solutions were irradiated to different doses by 1 MeV electron beams, and redox reactions of THA/FLO and radicals of · OH, e aq − and • H were investigated under various conditions. The results showed that at 8 kGy, the decomposition rate of THA and FLO was 97.2% and 98.5%, respectively. Quantitative and qualitative analysis indicated that · OH played a key role in E-beam degradation of the THA and FLO in aqueous solutions, and e aq − and • H radicals could initiate the degradation, too. Seven primary products of the THA and FLO degradation were identified. These indicate that E-beam radiation is an effective method to reduce THA and FLO in aqueous solutions. Thiamphenicol Florfenicol E-beam irradiation Mechanism References Schnick R A , Alderman D J , Armstrong R , et al . Bull Eur Assoc Fish Pathol , 1997 , 17 : 251 - 260 . Bull Eur Assoc Fish Pathol Sapkota A R , Kucharski M , Burke J , et al . Environ Int , 2008 , 34 : 1215 - 1226 . Environ Int Murray T R , Downey K M , Yunis A A . J Lab Clin Med , 1983 , 102 : 926 - 932 . J Lab Clin Med Boxall A B A , Fogg L A , Baird D J , et al . Final Report to the UK Environment Agency , 2005 . Final Report to the UK Environment Agency Code of Federal Regulations , Washington D C , 2002 , Chapter 556 , 283 . Code of Federal Regulations Committee for Veterinary Medicinal Products , the European Agency for the Evaluation of Medicinal Products . Florfenicol (extension to pigs), Summary Report , 1999 . Florfenicol (extension to pigs), Summary Report Agricultural Department of P.R. China . Bulletin No.235 , Agricultural Department of P. R. China, People’s Republic of China , 2002 . Bulletin No.235 Feng J B , Jia X P , Li L D . Aquaculture , 2008 , 276 : 29 - 35 . Aquaculture Kaptein B , van Dooren T J G M , Boesten W H J , et al . Org Process Res Dev , 1998 , 2 : 10 - 17 . Org Process Res Dev Ternes T A . Water Res , 1998 , 32 : 3245 - 3260 . Water Res Ingerslev F , Torang L , Loke M L , et al . Chemosphere , 2001 , 44 : 865 - 872 . Chemosphere Chatzitakisa A ., Berberidoua C , Paspaltsisb I. , et al . Water Res , 2008 , 42 : 386 - 394 . Water Res Pouliquen H , Delpepee R , Larhantec V M , et al . Aquaculture , 2007 , 262 : 23 - 28 . Aquaculture Bolton J R , Valladares J E , Cooper W J , et al . J Adv Oxid Technol , 1998 , 3 : 174 - 181 . J Adv Oxid Technol Leitner K N V , Guilbault I , Legube B . Radiat Phys Chem , 2003 , 67 : 41 - 49 . Radiat Phys Chem Martin D I , Margaritescu I , Cirstea E. et al . Vacuum , 2005 , 77 : 501 - 506 . Vacuum Buxton G V , Greenstock C K , Helman W P , et al . J Phys Chem Ref Data , 1988 , 17 : 513 - 886 . J Phys Chem Ref Data Lee B , Lee M . Environ Sci Technol , 2005 , 39 : 9278 - 9285 . Environ Sci Technol Getoff N . Radiat Phy Chem , 1996 , 4 : 581 - 593 . Radiat Phy Chem Georg B , Thomas O , Chemosphere , 1995 , 30 : 1781 - 1790 . Chemosphere Adewuyi Y G , He X , Shaw H , et al . Chem Eng Commun , 1999 , 174 : 21 - 51 . Chem Eng Commun Pignatello J , Oliveros E , MacKay A , Crit Rev Environ Sci Technol , 2006 , 36 : 1 - 84 . Crit Rev Environ Sci Technol Kapoor S , Varshney L , J Phys Chem A , 1997 , 101 : 7778 - 7782 . J Phys Chem A 10.13538/j.1001-8042/nst.21.334-338 Supported by National Natural Science Foundation of China (No. 40973073, 40830744) ; Project of Leading Disciplinary Studies in Shanghai (No.S30109) ; National Key Technology R&D Program in the 11th Five-year-plan of China (No.2008BAC32B03, 2009BAA24B04) ; Municipal Natural Science Foundation of Shanghai (No. 09ZR1411300) 2010-04-08 2010-12-20 2021-01-19 2010 Nuclear Science and Techniques 06 21