SYNTHESIS OF (2-³H) BROMOACETAMIDE

SYNTHESIS OF (2- 3 H) BROMOACETAMIDE 1 first-author 1 1 Institute of Nuclear Research, Academia Sinica, Shanghai 201800, China Institute of Nuclear Research, Academia Sinica, Shanghai 201800, China (2- 3 H) bromoacetamide, a radiotracer of oncomelanicide for various biological studies, has been synthesized by multiple organic reactions from 3 H- sodium acetate. The radiochemical purity checked by radio- HPLC was 95% and the specific activity was 11.3GBq/mmol (305mCi/mmol). Moreover, 3 H- NMR spectrum indicated that all tritium atoms were labelled on the position 2. Bromoacetamide Tritium labelled REFERENCES Arthur Murray , III and D. Lloyd Williams , Organic synthesis with isotopes , Interscience Publisher, Inc ., New York , 1958 , p. 412 . Organic synthesis with isotopes ibid , 1958 , p. 328 . Zhao Xialing and Liu Jingzhi , Atomic Energy Science and Technology (in Chinese) , 17 ( 1983 ), 734 . Atomic Energy Science and Technology (in Chinese) 1991-11-01 2021-02-05 1991 Nuclear Science and Techniques 4 2