Research Highlight Videos15 Dec 2023
Shanghai's Proton Therapy:A Leap Towards Targeted Cancer Treatment
Man-Zhou Zhang, De-Ming Li, Li-Ren Shen, Hai-Rong Zhang, Zhi-Ling Chen, Han-Wen Du, Ming Gu, Rui Li, De-Kang Liu
Proton therapySynchrotronSlow extractionGantryBeam delivery system
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Keywords:


SAPT,proton therapy, synchrotron, slow extraction, gantry, beam delivery system


The Novelty

A synchrotron-based proton therapy facility has been inaugurated in Shanghai, elevating the standards of cancer treatment in the region.


In a clinical trial encompassing 47 patients, the research illuminated the facility's prowess: both the synchrotron and the beam delivery system operated at their expected peak performances.


The results are promising whereby the facility's beam delivery system and other technical components consistently met the anticipated performances.


With its success, Shanghai's innovative facility offers hope for enhanced therapeutic methods in cancer care and propels the global medical community toward broader applications and expansions of proton therapy.


The Background


Proton therapy is an innovative approach to cancer treatment.

It is distinguished by its utilization of the Bragg peak—a phenomenon where protons and heavy ions expel most of their energy at the end of their travel in matter.

This mechanism ensures targeted treatment of tumors with minimal damage to surrounding tissues.

Despite its advantages, prior models of proton therapy utilized accelerators like cyclotrons, which generated excessive radiation and radioactivation.

Recognizing these shortcomings, the Shanghai research team introduced the synchrotron-based facility.

This solution is designed to deliver the required beam energy directly.



The SDG impact


According to the World Health Organization, cancer is the second leading cause of death globally, underscoring the urgency for innovative treatments.

The Shanghai advance proton therapy (SAPT) facility in Shanghai directly addresses this pressing concern, heralding a safer and more effective approach to cancer treatment.

This initiative aligns seamlessly with UNSDG 3: Good Health and Well-being, by advancing global health standards.

Furthermore, by fostering innovation in healthcare infrastructure, the facility embodies the principles of SDG 9: Industry, Innovation, and Infrastructure.


Graphical Abstract


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