Simulation of an imaging system for internal contamination of lungs using MPA-MURA coded aperture collimator

Ting Zhang; Lei Wang; Jing Ning; Wei Lu; Xiao-Fei Wang; Hai-Wei Zhang; Xian-Guo Tuo

doi:10.1007/s41365-021-00849-3

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Simulation of an imaging system for internal contamination of lungs using MPA-MURA coded aperture collimator

NUCLEAR ELECTRONICS AND INSTRUMENTATION | Updated：2021-03-12

- Simulation of an imaging system for internal contamination of lungs using MPA-MURA coded aperture collimator
- Nuclear Science and Techniques Vol. 32, Issue 2, Article number: 17(2021)
- Affiliations：
  
  1.Chengdu University of Technology, Chengdu 610059, China
  2.Sichuan University of Science & Engineering, Zigong 643000, China
  3.Beijing Institute of Radiation Medicine, Beijing 100850, China
- Author bio：
  
  Corresponding author, wl@cdut.edu.cn
- Funds：
- DOI：10.1007/s41365-021-00849-3
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Ting Zhang, Lei Wang, Jing Ning, et al. Simulation of an imaging system for internal contamination of lungs using MPA-MURA coded aperture collimator. [J]. Nuclear Science and Techniques 32(2):17(2021)
DOI：

Ting Zhang, Lei Wang, Jing Ning, et al. Simulation of an imaging system for internal contamination of lungs using MPA-MURA coded aperture collimator. [J]. Nuclear Science and Techniques 32(2):17(2021) DOI： 10.1007/s41365-021-00849-3.

摘要

Abstract

The nuclides inhaled during nuclear accidents usually cause internal contamination of the lungs with low activity. Although a parallel-hole imaging system, which is widely used in medical gamma cameras, has a high resolution and good image quality, owing to its extremely low detection efficiency, it remains difficult to obtain images of inhaled lung contamination. In this study, the Monte Carlo method was used to study the internal lung contamination imaging using the MPA-MURA coded-aperture collimator. The imaging system consisted of an adult male lung model, with a mosaicked, pattern-centered, and anti-symmetric MURA coded-aperture collimator model and a CsI(Tl) detector model. The MLEM decoding algorithm was used to reconstruct the internal contamination image, and the complementary imaging method was used to reduce the number of artifacts. The full width at half maximum of the I-131 point source image reconstructed by the MPA-MURA coded-aperture imaging reached 2.51 mm, and the signal-to-noise ratio of the simplified respiratory tract source (I-131) image reconstructed through MPA-MURA coded-aperture imaging was 3.98 dB. Although the spatial resolution of MPA-MURA coded aperture imaging is not as good as that of parallel-hole imaging, the detection efficiency of PMA-MURA coded-aperture imaging is two orders of magnitude higher than that of parallel hole collimator imaging. Considering the low activity level of internal lung contamination caused by nuclear accidents, PMA-MURA coded-aperture imaging has significant potential for the development of lung contamination imaging.

关键词

Keywords

Lung internal contaminationMPA-MURAMonte CarloMLEMSpatial resolutionDetection efficiency

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Related Institution

Advanced Energy Science and Technology Guangdong Laboratory

School of Nuclear Science and Technology, University of Chinese Academy of Sciences

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National Supercomputing Center in Chengdu

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