Rui-Bo ZHONG, Yu-Shuang LIU, Ping ZHANG, et al. A facile method to build a proton nanosensor with neutral to basic pH sensitive range. [J]. Nuclear Science and Techniques 25(4):040503(2014)
DOI:
Rui-Bo ZHONG, Yu-Shuang LIU, Ping ZHANG, et al. A facile method to build a proton nanosensor with neutral to basic pH sensitive range. [J]. Nuclear Science and Techniques 25(4):040503(2014) DOI: 10.13538/j.1001-8042/nst.25.040503.
A facile method to build a proton nanosensor with neutral to basic pH sensitive range
Bio-nanosensors (Bio-NSs) have attracted much attention recently due to their unique properties. Among all of the bio-NSs, the intracellular proton sensor is significant for biomedicine studies and clinic diagnosis. Proton nanosensors (PNSs) with different pH sensitive ranges could satisfy different research requirements. Here we report a facile method to build a PNS with a neutral to basic pH sensitive range, in which the commercial pH indicator, fluoresceinamine (FA), was covalently coupled to the carboxylic-rich amphiphilic polymer (AP) coated gold nanoparticles (AuNPs).