An online monitor ionization chamber used in particle therapy

An online monitor ionization chamber used in particle therapy 1 2 corresp first-author Corresponding author. E-mail address: tangbin@impcas.ac.cn Corresponding author. E-mail address: tangbin@impcas.ac.cn tangbin@impcas.ac.cn 1 1 1 2 1 1 2 1 2 1 2 1 2 1 2 1 1 1 2 1 1 1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China Graduate University of Chinese Academy of Sciences, Beijing 100049, China Graduate University of Chinese Academy of Sciences, Beijing 100049, China The clinical trials of tumor therapy using heavy ions beam 12 C are now in progress at Institute of Modern Physics in Lanzhou. In order to achieve the precise radiotherapy with the high energy 12 C beam in active pencil beam scanning mode, we have developed an ionization chamber(IC) as an online monitor for beam intensity and also a dosimeter after calibration. Through the choosing of working gas and voltage, optimizing of the electrics and the read-out system, calibrating the linearity, the detector system provide us one of the simple and highly reliable way to monitoring the beam during the active pencil beam scanning treatments. The measurement results of this detector system show that it could work well under the condition of high energy 12 C beam in active pencil beam scanning mode. Heavy ion beam therapy Integral ionization chamber Irradiation dose Absorb dose References Tobias C A , Anger H O , Lawrence J H . Am J Roentgenol Ther Nucl Med , 1952 , 67 ( 1 ): 1 - 27 . Am J Roentgenol Ther Nucl Med Particle therapy facilities in operation (March 2009) , available at http://ptcog.web.psi.ch/ptcentres.html Particle therapy facilities in operation (March 2009) Amaldi U . Phys Med , 1998 , 14 : 76 - 84 . Phys Med Eickhoff H , Böhne D , Debus J , et al . The proposed accelerator facility for light ion cancer therapy in Heidelberg Proc . 1999 Particle Accelerator Conf . New York , 1999 : 2513 - 2515 . The proposed accelerator facility for light ion cancer therapy in Heidelberg Proc Carstro J R . Radiate Environ Biophys , 1995 , 34 : 45 - 48 . Radiate Environ Biophys TANG Bin , HU Zhengguo , XU Zhiguo , et al . Nucl Electron Detect Technol (in Chinese) , 2008 , 28 ( 4 ): 699 - 701 . Nucl Electron Detect Technol (in Chinese) MAO Ruishi , XIAO Guoqing , ZHAO Tiecheng , et al . High power laser and particle beams (in Chinese) , 2008 , 20 ( 9 ): 1537 - 1540 . High power laser and particle beams (in Chinese) Lyman J T , Awschalom M , Berardo P , et al . Protocol for heavy charged-particle therapy beam dosimeter. AAPM Report No. 16 , 1986 : 13 - 15 . Protocol for heavy charged-particle therapy beam dosimeter. AAPM Report No. 16 Brusasco C , Voss B , Schardt D M , et al . Nucl Instrum Methods Phys Res B , 2000 , 168 : 578 - 592 . Nucl Instrum Methods Phys Res B IAEA , Absorbed dose determination in external veam radiotherapy, IAEA Technical reports Serial No. 398 , International Atomic Energy Agency , Vienna , 2000 : 57 - 63 . Absorbed dose determination in external veam radiotherapy, IAEA Technical reports Serial No. 398 10.13538/j.1001-8042/nst.20.177-180 Supported by the National Nature Science Foundation of China (No. 10305015, No.10475098) and the Major Program of the Chinese Academy of Science (No. O701050YZD) 2008-11-21 2009-06-20 2021-01-19 2009 Nuclear Science and Techniques 03 20