DOSE RESPONSE CURVE OF ⁶⁰Co FOR PREMATURE CONDENSED CHROMOSOME FRAGMENTS OF HUMAN LYMPHOCYTES

DOSE RESPONSE CURVE OF 60 Co FOR PREMATURE CONDENSED CHROMOSOME FRAGMENTS OF HUMAN LYMPHOCYTES 1 first-author 1 1 1 Department of Radial Genetic Research, Suzhou Medical College, Suzhou, 215007 Department of Radial Genetic Research, Suzhou Medical College, Suzhou, 215007 The dose-response curves obtained by premature condensed chromosome (PCC) and conventional cellular genetic methods can be represented by two linear equations. The ratio of the slopes, K PCC /K M1 , is about 28. In comparison to the conventional method, the PCC method has many advantages; e.g. it is faster, simpler, more sensitive and accurate. Its significance in the study of radiation damage is also discussed. Dose response relationships 60 Co Men Lymphocytes Premature condensed chromosome References Johnson R T , Rao P N . Nature , 1970 ; 226 : 717 Nature Pantelias G E , Maillie H D . Somatic Cell Genetic , 1983 ; 9 ( 5 ): 533 Somatic Cell Genetic Crossen P E , Morgan W F . Exp Cell Res , 1977 ; 104 : 453 Exp Cell Res Pantelias G E , Maillie H D . Radiat Res , 1984 ; 99 : 140 Radiat Res Bertsche U . Radiat Environ Biophys , 1988 ; 27 : 201 Radiat Environ Biophys Jin Cut Zhen . Irradiation Safeguard , 1988 ; 8 ( 4/5 ): 391 Irradiation Safeguard Cornforth M N , Bedford J S . Science , 1983 ; 222 : 1141 Science Maillie H D , Baker J V . Health Physics , 1986 ; 51 : 672 Health Physics 1995-02-20 1995-08-01 2021-02-05 1995 Nuclear Science and Techniques 3 6