Pre-exposure effect of low-dose ¹⁶O⁸⁺ or γ-rays on testicular endocrine of mice

Pre-exposure effect of low-dose 16 O 8+ or γ -rays on testicular endocrine of mice 1 corresp first-author Author for correspondence. Tel.0931-8854897, Fax.0931-8881100 Author for correspondence. Tel.0931-8854897, Fax.0931-8881100 1 1 1 1 1 1 1 1 1 1 2 2 Institute of Modern Physics, the Chinese Academy of Sciences, Lanzhou 730000 Institute of Modern Physics, the Chinese Academy of Sciences, Lanzhou 730000 Department of Biology, Lanzhou University, Lanzhou 730000 Department of Biology, Lanzhou University, Lanzhou 730000 The testes of the B6C3F1 hybrid strain mice were irradiated with 0.05 Gy of 16 O 8+ ion/ 60 Co γ -ray as the pre-exposure dose, and were then irradiated with 2 Gy of 16 O 8+ ion/ 60 Co γ -ray as challenging irradiation dose at 4h after pre-exposure. The results show that irradiation of mouse testes with 2 Gy of 16 O 8+ ion or 60 Co γ -ray significantly diminished mouse body mass, testis mass and serum testosterone. However, pre-exposure with a low-dose (0.05 Gy) significantly reduces this kind of effect. The relative biological effectiveness of 16 O 8+ ion was calculated with respect to 60 Co γ -ray for the induction of reduction in body mass, testis mass and serum testosterone to be 1.71, 1.81 and 1.42, respectively. 16 O 8+ ion Pre-exposure with low-dose Endocrine capacity Mouse testes Adaptive response References Luckey T O. Health Phys , 1982 , 43 : 771 Health Phys Planel H , Sdeilhavonp J P. Tixador R. et al . Health Phys , 1987 , 52 : 571 Health Phys Wolff S , Afzal V , Wiencke J K et al . Int J Radiat Biol , 1988 , 53 : 39 Int J Radiat Biol Wei Z Q , Liu Y Y , Wang G L et al . Nucl Tech (in Chinese) , 1991 , 14 : 341 Nucl Tech (in Chinese) Berline D L. Ellis La G C , Taylor G N. Radiat Res , 1964 , 22 : 345 Radiat Res Binhammer R T. Radiat Res , 1967 , 30 : 676 Radiat Res Yamaoka K , Edamatsu R , Mori A. Free Radical Biol Med , 1991 , 11 : 299 Free Radical Biol Med Yamaoka K , Edamatsu R , Itoh T et al . Free Radical Biol Med , 1994 . 16 : 529 Free Radical Biol Med Bartosz G , Leyko W , Fried R . Experientia , 1997 , 35 : 1194 Experientia Shiraish N , Aouo K , Utsumi K. Radiat Res , 1983 , 95 : 298 Radiat Res The Project Supported by China Postdoctoral Sciencc Foundation. Head's Science Foundation of the Chinese Academy of Sciences, and Climbing Plan B of the National Sciences and Technology Committee 1997-08-11 1998-02-01 2021-02-05 1998 Nuclear Science and Techniques 1 9