GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging

Ren-Yao Wu; Chang-Ran Geng; Feng Tian; Zhi-Yang Yao; Chun-Hui Gong; Hao-Nan Han; Jian-Feng Xu; Yong-Shun Xiao; Xiao-Bin Tang

doi:10.1007/s41365-023-01199-y

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GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging

ACCELERATOR, RAY TECHNOLOGY AND APPLICATIONS | Updated：2023-06-07

- GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging
- GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging
- 核技术（英文版） 2023年34卷第4期文章编号：52
- Affiliations：
  
  1.Department of Nuclear Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
  2.Department of Engineering Physics, Tsinghua University, Beijing 100084, China
  3.School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
  4.JYAMS PET Research and Development Limited, Nanjing 211100, China
- Author bio：
  
  * gengchr@nuaa.edu.cn
  tangxiaobin@nuaa.edu.cn
- Funds：
  
  National Natural Science Foundation of China(12220101005);Natural Science Foundation of Jiangsu Province(BK20220132);Primary Research and Development Plan of Jiangsu Province(BE2019002-3);Fundamental Research Funds for Central Universities(NG2022004);Foundation of the Graduate Innovation Center in NUAA(xcxjh20210613)
- DOI：10.1007/s41365-023-01199-y
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GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging[J]. 核技术（英文版）, 2023,34(4):52

Ren-Yao Wu, Chang-Ran Geng, Feng Tian, et al. GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging[J]. Nuclear Science and Techniques, 2023,34(4):52
GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging[J]. 核技术（英文版）, 2023,34(4):52 DOI： 10.1007/s41365-023-01199-y.

Ren-Yao Wu, Chang-Ran Geng, Feng Tian, et al. GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging[J]. Nuclear Science and Techniques, 2023,34(4):52 DOI： 10.1007/s41365-023-01199-y.

摘要

Abstract

A novel and fast three-dimensional reconstruction method for a Compton camera and its performance in radionuclide imaging is proposed and analyzed in this study. A conical-surface sampling back-projection method with scattering angle correction (CSS-BP-SC) can quickly perform the back-projection process of the Compton cone and can be used to precompute the list-mode maximum likelihood expectation maximization (LM-MLEM). A dedicated parallel architecture was designed for the graphics processing unit acceleration of the back projection and iteration stage of the CSS-BP-SC-based LM-MLEM. The imaging results of the two-point source Monte Carlo (MC) simulation demonstrate that by analyzing the full width at half maximum along the three coordinate axes, the CSS-BP-SC-based LM-MLEM can obtain imaging results comparable to those of the traditional reconstruction algorithm, that is, the simple back-projection-based LM-MLEM. The imaging results of the mouse phantom MC simulation and experiment demonstrate that the reconstruction results obtained by the proposed method sufficiently coincide with the set radioactivity distribution, and the speed increased by more than 664 times compared to the traditional reconstruction algorithm in the mouse phantom experiment. The proposed method will further advance the imaging applications of Compton cameras.

关键词

Keywords

Compton cameraThree-dimensional reconstructionRadionuclide imagingGPU

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