Development of X-ray dark-field imaging towards clinical application

SYNCHROTRON TECHNOLOGY AND APPLICATIONS

Development of X-ray dark-field imaging towards clinical application

ANDO Masami，

HASHIMOTO Eiko，

HASHIZUME Hiroyuki，

HYODO Kazuyuki，

INOUE Hajime，

ISHIKAWA Tetsuya，

KUNISADA Toshiyuki，

MAKSIMENKO Anton，

PATTANASIRIWISAWA Wanwisa，

RUBENSTEIN Edward，

ROBERSON Joseph，

SHIMAO Daisuke，

SUGIYAMA Hiroshi，

TAKEDA Ken，

UENO Ei，

WADA Hiroshi

Nuclear Science and Techniques

Vol.15, No.3

pp.129-139

Published in print 01 Jun 2004

CLC：R814,O436

23100

Review of X-ray dark-field imaging under development is presented. Its goal is its application to clinical diagnosis of organs that have been invisible by the ordinary techniques. In order to clinically visualize tissues in detail one needs high contrast and high spatial resolution say ~50 μmm. This X-ray optics comprises a Bragg asymmetric monochro-collimator and a Bragg case or a Laue case filter with capability of analyzing angle in a parallel position. Their diffraction index is 4,4,0 and the X-ray energy 35 keV (λ= 0.0354 nm). The filter has 0.6 mm thickness in the Bragg case or 1.075 mm or 2.15 mm thickness in the Laue case. Under this condition only the refracted X-rays from object can transmit through the filter while the beam that may receive absorption and/or phase change will not. Soft tissues at human joints thus taken show high contrast images so that the DFI is promising for clinical diagnosis. Preliminary X-ray absorption images of another clinical candidates of ear bones are also shown.

X-ray dark-field imagingX-ray bright-field imagingBragg asymmetric monochro-collimatorBragg case filterLaue case filterClinical diagnosis

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