logo

A QTC-based signal readout for position-sensitive multi-output detectors

NUCLEAR ELECTRONICS AND INSTRUMENTATION

A QTC-based signal readout for position-sensitive multi-output detectors

Wei Zhou
Zhi-Ming Zhang
Dao-Wu Li
Pei-Lin Wang
Bao-Tong Feng
Xian-Chao Huang
Ting-Ting Hu
Xiao-Hui Li
Yan Chen
Ying-Jie Wang
Yan-Tao Liu
Yi-Wen Zhang
Shi-Feng Sun
Xiao-Yue Gu
Ming-Jie Yang
Xiong Xiao
Long Wei
Nuclear Science and TechniquesVol.27, No.5Article number 119Published in print 20 Oct 2016Available online 31 Aug 2016
34900

A new signal readout method for position-sensitive multi-output detectors, such as those in high energy spectroscopy measurement and nuclear imaging, was developed by combining the charge division circuit, summing circuit and charge-to-time conversion (QTC) circuit. The 64 outputs of a Hamamatsu H8500 position-sensitive photomultiplier tube (PSPMT) were processed and three digital pulses were generated. The widths of digital pulses were determined using the time-to-digital converter (TDC) in an FPGA (Field Programmable Gate Array). The energy and position information of incident γ-rays is estimated based on the proportionality between the width of digital pulses and input charge created by γ photons. A prototype was built using discrete components and tested, and the energy and position resolutions were improved compared with that obtained with standard ADCs. This method greatly simplifies the front-end electronics and the digital interface. It enables a compact electronics system and an easy integration into an ASIC.

Signal readoutCharge-to-time conversionTime-to-digital converterH8500 PSPMT

1 Introduction

In recent years, position-sensitive multi-output detectors to record the energy and position information of nuclear radiations have been widely used in high energy physics [1-6], PET/SPECT (positron emission tomography/single photon emission computed tomography), and gamma camera for radiation detection [7-12]. The Hamamatsu H8500 is a compact flat panel position-sensitive photomultiplier (PSPMT) based on 12-stage dynode electronic amplification and contains an anode matrix of 8×8 anodes spaced at 6 mm pitch. With an 89% effective active area coverage and high spatial resolution on a 52 mm×52 mm square panel, H8500 PSPMT is convenient for applications in small animal imaging, gamma camera, scinti-mammography and 2D radiation monitor [13-17]. Conventionally, Its current signals are processed by a preamplifier and a shaping circuit, and the shaped signals are converted to digital signals using Analog-to-Digital Converters (ADCs) before the digital signals are fed into back-end electronics such as a Field Programmable Gate Array (FPGA). The energy and positioning information of nuclear radiations can be obtained by a special algorithm installed in the FPGA or a computer.

QTC (Charge-to-Time conversion) is an effective way of transforming the detected information. The amplitude of an input signal from the detector is transformed to width of the digital pulse, is then measured by time-to-digital converter (TDC) in the FPGA. Without external ADCs, QTC is advantageous in its lower power consumption and simplified front-end electronics. It contributes to higher levels of channel density, as the routing between the front-end and back-end electronics is simplified. Owing to these advantages of QTC and the implementation of high-resolution TDC in the FPGA [18], different types of QTC circuits have been developed in laboratories, such as the TOF (Time-Of-Flight) detectors in BES (Beijing Spectrometer) III [19], time-based readout ASIC [20] and the pulse width modulation for PET application [21].

In this paper, we propose a novel readout method based on combining the charge division circuit, summing circuit and QTC circuit for position-sensitive multi-output detectors. The Hamamatsu H8500 PSPMT, coupled with LYSO crystal (cerium-doped lutetium yttrium orthosilicate), is used as position-sensitive multi–output detector module. The readout method is described in detail, A prototype circuit is designed, and performance of the circuit is tested. This method can be applied in multi-channel readout of position-sensitive detectors used in high energy spectroscopy measurements and nuclear imaging, including industry imaging and medical imaging. Also, this readout method may be applicable for other position-sensitive detectors [10], such as pixelated silicon photomultiplier (SensL-C-60035) for high energy spectroscopy.

2 Methods

2.1 Signal processing flow

A readout method is proposed to acquire energy and positioning information of incident γ photons. The concept of this method is shown in Fig.1. The incident γ photons deposit energy in the LYSO crystal to create fluoresce immediately, which is converted to photo-electrons on  photocathode of the H8500 PSPMT to, generate current signals.

Fig. 1
The concept of QTC-based readout for PSPMT.
pic

The current signals from the PSPMT are processed by the charge division module (CDM) [22], which works to reduce the number of readout channels from sixty-four to IA, IB, IC, and ID, which are fed into the summing module (SM) (Fig.2a) designed to convert input current signals to voltage and reduce the number of output channels from four to VX, VY and VE. The VX, VY and VE are fed into the charge-to-time conversion module (QTCM) (Fig. 2b) composed of charge-to-time circuits and high speed comparators. The output digital pulses of TX, TY and TE (LVTTL levels) are finally generated with pulse width proportional to the integral of the input signal. The pulse width is measured using a TDC in the FPGA, and the data are transmitted to the computer via a gigabit network.

Fig. 2.
The circuits of SM(a) and QTCM (b).
pic
2.2 Principle and circuit design

The SM circuit in Fig.2(a) is composed of current-sensitive preamplifiers, and inverting summing circuits with their gain being set to 1. So we can obtain Eqs.(1-3):

VE= (IA+IB+IC+ID)RS, (1) VX= (IA+IB)RS, (2) VY= (IB+IC)RS. (3)

The QTCM circuit in Fig. 2(b) is composed of charge-to-time conversion circuits and high speed discriminators. The charge-to-time conversion circuit is designed according to the original QTC principle of the TOF detectors in BESIII. [19] Some appropriate improvement is made for the application in position sensitive detector. The comparator (ADCMP602) output digital pulse (LVTTL) can be directly fed into FPGA without any level translation.

For the signal flow of VE ~ VTE ~ TE, the negative input signal (VE) charges CT via RT and the constant source IT also discharges CT. The clamping diode (D) provides a DC route for charge-to-time conversion in order to clamp the output VTE to the baseline (VB) of about −300 mV at VE =0. The charge Qin fed into CT is proportional to the integral of the input signal (VE). So the discharge time interval TE can be described as:

TE=Qin/IT=aVEdt+b , (4)

where a and b are coefficients associated with IT, RT, VB and the threshold voltage of comparator VREF. Note that the output VTE will maintain VB and TE is zero, if charging current IE is less than the discharge current IT. So there is a tradeoff in pile-up at high event rates and the dynamic range. Specifically, the discharge current should be as small as possible for wide dynamic range which also lead to pile-up in high event rates.

Assuming that QA, QB, QC and QD are integrals of the current signals IA, IB, IC and ID, we have:

QE= (QA+QB+QC+QD) Eγ  , (5)

where QE is the total charge collected by PSPMT, which is proportional to energy of the incident γ photons (Eγ). Combining Eqs. (1), (4) and (5), we can obtain:

QE=ATE+B, (6)

where A and B are coefficients associated with the SM and QTCM, and QE can represent the energy of incident γ photons. Similarly, we can obtain Eqs.(7) and (8):

QX=ATX+B, (7) QY=ATY+B . (8)

So the γ photon position can be determined by Eqs.(9) and (10):

X=(QA+QB)/QE= (ATX+B)/(ATE+B) , (9) Y=(QB+QC)/QE= (ATY+B)/(ATE+B)  . (10)

The outputs (TE, TX and TY) are received directly by the FPGA and measured by the TDC (64ps resolution) in the FPGA. The data TE, TX and TY are transmitted to the computer through the network and the energy and position information of the γ photons can be obtained using Eqs. (6), (9) and (10).

The experimental circuit was designed and tested with the H8500 PSPMT. Fig.3(a) is a photo of the circuit, with Parts 1, 2 and 3 being the CDM, SM and QTCM, respectively; while Fig.3(b) shows the VE, VTE and TE signals generated by the experiment circuit (captured by Tektronix DPO 3054 oscilloscope).

Fig.3.
The experimental circuit (a) and the signals of VE, VTE and TE captured by oscilloscope (b). 1, CDM; 2, SM; 3, QTCM.
pic

3 Experimental tests and results

Performance of the experimental circuit was tested with the Hamamatsu H8500 and an 11×11 array of LYSO crystals of 3.5 mm ×3.5 mm ×20 mm. Fig.4 shows the LYSO crystal array, H8500 PSPMT and the experimental platform including high- and low-voltage sources, the experimental circuit, data acquisition board for TDC and computer.

Fig.4.
The experimental set-up to test the circuit.
pic
3.1 Linearity test of QTCM

In the linearity test of QTCM, pulses with adjustable amplitude (200 mV per step) from a function generator (AFG3252) were sent to the input stage of QTCM with the discharge current of 100 μA. A group of digital pulses was generated, and their time widths were obtained using TDC. As shown in Fig.5, the QTCM has a large dynamic range from 300 mV to 4 V, with the maximum time width of about 9 μs, the fitting coefficient of R2 = 0.9997, and the integrated nonlinearity of 1.31%.

Fig.5.
Linear fitting of the test results.
pic
3.2 Energy spectrum test

The H8500 PSPMT coupled with a single 3.5 mm ×3.5 mm ×20 mm LYSO crystal was used to obtain the energy spectrum with 137Cs and 22Na sources. The high voltage source was −750V and the discharge current was 100 μA. Under the same experimental conditions, we obtained the energy spectrum by using the commercial 12-bit 40-MHz ADC (ADS5282 from TI) with the signal VE being fed into the input of the ADC. Fig.6 compares the spectra obtained with the ADC and the QTC circuit, after appropriate scaling.

Fig.6.
Gamma-ray spectra of 137Cs (a) and 22Na (b) obtained with an ADC system and the QTC-based circuit.
pic

From Table 1, one sees that energy resolutions of the peaks at 511 keV, 662 keV and 1.27 MeV by the two methods are close to each other. Although some distortion appears in low energy regions of both spectra, it can be seen that input signals cannot be detected by the QTC circuit if the input charge current is less than the discharge current IT, as explained in Section 2.2. So a tradeoff between dynamic range and dead time has to be found in practical spectrum measurements.

Table 1
Energy resolutions (in %FWHM) of ADC system and QTC-based circuit
Gamma-rays ADC system QTC-based circuit
511 keV(137Cs) 14.62 15.42
662 keV(22Na) 13.05 13.86
1.27 MeV(22Na) 8.89 9.75
Show more
3.3 Positioning resolution test

The H8500 PSPMT coupled with an 11×11 array of 3.5 mm ×3.5 mm ×20 mm LYSO crystal, and a 137Cs source, were used to test the position resolution. The high voltage was −750 V, and the discharge current was 100 μA. Fig.7(a) shows the flood histogram and profile histogram, with the peak-to-valley ratio of about 5:1. It can be seen that the 11×11 crystals in the array can all be identified clearly. In comparison, using the ADC method, with the ADS5282 and the same combination of the H8500 PSPMT and LYSO crystal array, the profile histogram (Fig.7b) has a peak-to-valley ratio of about 6:1.

Fig.7
The raw flood histogram (left) and the raw profile histogram (right) by the QTC (a) and ADC (b) methods.
pic
3.4 Linearity test of system

Gamma-ray spectra of 137Cs, 22Na and 60Co were measured with the system (Fig.8a), and linearity of the test pulses generated by the function generator (AFG3252) was checked (Fig.8b), with the fitting coefficient of R2 =0.9989 and the integrated nonlinearity of 1.38%, while it is 0.95% in the energy range using the ADC-based system (ADS5282).

Fig.8
Gamma-ray spectra (a) of 137Cs, 22Na and 60Co, and the peak linearity fit (b).
pic
3.5 Stability test of system

To test stability and credibility, the system was measuring the 137Cs source at room temperature for 48 hours, recording a γ-ray spectrum every three hours. From Fig.9, the maximum deviation of peak position in 50 hours is 0.32%.

Fig.9
Stability of 662 keV peak position in 48 hours. The error bars are FWHM of gamma-ray peak.
pic
3.6 Discussion

The readout performance of the experimental circuit for position-sensitive detectors indicates that the QTC-based circuit has good linearity and energy resolution, which are close to the results of conventional ADC-based systems. We noticed some distortion in low energy region of the spectra using the QTC method, so the best tradeoff between dynamic range and dead time should be evaluated. In the position resolution test of QTC-based circuit, all the crystals can be identified with a peak-to-valley ratio of about 5:1 though the flood histogram distorted slightly compared to that of the ADC method.

However, the proposed method does not outperform ADC-based systems in linearity, with integrated nonlinearities of 1.38% and 0.95% for the QTC and ADC methods, respectively. In fact, the QTCM output width T is not simply proportional to the input charge Q, some complicated calibrations should be performed for better energy and position resolutions, which means a more complicated system. The original QTC calibration method has been described in detail for BESIII’s TOF detector in Ref.[19]. To simplify the whole system including hardware and software design for the application in position sensitive detector, the QTCM output width T is considered to be proportional to the input charge Q in this paper and the results are acceptable. An advantage of the proposed method is that large number of interface lines between ADCs and FPGA can be simplified. It contributes to great simplification of electronic system and low power consumption (~100 mW per channel for ADC and ~30 mW per channel for QTC).

4 Conclusion

In this paper, we propose an electronic readout method for position sensitive detectors, using experimental circuits composed of a CDM, a SM and a QTCM designed and tested with the Hamamatsu H8500 PSPMT and LYSO crystals. Without using ADCs, this method greatly simplifies the digital interface to FPGA for a compact electronic system, leading to low power consumption and beneficial for the integration in a monolithic chip. The experimental results of circuit linearity, energy spectrum, flood histogram and stability show that this method is suitable for multi-channel readout of position sensitive detectors and may be used for the applications to high energy spectroscopy measurements and nuclear imaging.

References
[1] R. Engels, U. Clemens, G. Kemmerling et al.,

Position-sensitive detectors of the detector group at Julich

. Nucl. Instrum. Methods A. 604, 147-149 (2009). DOI: 10.1016/j.nima.2009.01.090
Baidu ScholarGoogle Scholar
[2] T. Matsumoto, S. Korpar, I. Adachi et al.,

Studies of proximity focusing RICH with an aerogel radiator using flat-panel multi-anode PMTs (Hamamatsu H8500)

. Nucl. Instrum. Methods A. 521, 367-377 (2004). DOI: 10.1016/j.nima.2003.11.384
Baidu ScholarGoogle Scholar
[3] M. Petris, M. Petrovici, V. Catanescu et al.,

Two-dimensional position sensitive transition radiation detector

. Nucl. Instrum. Methods A. 714, 17-23 (2013). DOI: 10.1016/j.nima.2013.02.039
Baidu ScholarGoogle Scholar
[4] R. A. Montgomery, M. Hoek, V. Lucherini et al.,

Investigation of Hamamatsu H8500 phototubes as single photon detectors

. Nucl. Instrum. Methods A. 790, 28-41(2015). DOI: 10.1016/j.nima.2015.03.068
Baidu ScholarGoogle Scholar
[5] S. Vaintraub, M. Hass, H. Edri et al.,

Large area position sensitive β-detector

. Nucl. Instrum. Methods A. 777, 36-42 (2015). DOI: 10.1016/j.nima.2014.12.089
Baidu ScholarGoogle Scholar
[6] R. Pestotnik, I. Adachi, S. Fratina et al.,

Proximity focusing RICH with flat panel PMT (Hamamatsu H8500) as photon detector and aerogel radiator

. Nucl. Instrum. Methods A. 525, 158-162 (2004). DOI: 10.1016/j.nima.2004.03.040
Baidu ScholarGoogle Scholar
[7] Philippe Després, William C. Barber, Tobias Funk et al.,

Investigation of a Continuous Crystal PSAPD-Based Gamma Camera

. IEEE Trans. Nucl. Sci. 53, 1643-1649 (2006). DOI: 10.1109/TNS.2006.875354
Baidu ScholarGoogle Scholar
[8] Y.F. Liao, Z.M. Zhang, D.W. Li et al.,

Preliminary study of depth of interaction measurement for a PET detector

. Chin. Phys. C. 35, 1070-1073 (2011). DOI: 10.1088/1674-1137/35/11/017
Baidu ScholarGoogle Scholar
[9] X.C. Huang, Z.M. Zhang, D.W. Li et al.,

Performance evaluation of a parallel-hole collimated detector module for animal SPECT imaging

. Chin. Phys. C. 35, 1162-1165 (2011). DOI: 10.1088/1674-1137/35/12/016
Baidu ScholarGoogle Scholar
[10] Y.J. Wang, Z.M. Zhang, D.W. Li et al.,

Design and performance evaluation of a compact, large-area PET detector module based on silicon photomultipliers

. Nucl. Instrum. Methods A. 670, 49-54 (2012). DOI: 10.1016/j.nima.2011.12.064
Baidu ScholarGoogle Scholar
[11] Y.T. Liu, Z.M. Zhang, D.W. Li et al.,

Depth discrimination method based on a multi-row linear array detector for push-broom Compton scatter imaging

. Applied Radiation and Isotopes. 82, 293-299 (2013). DOI: 10.1016/j.apradiso.2013.09.001
Baidu ScholarGoogle Scholar
[12] S.F. Sun, Z.M. Zhang, L. Shuai et al.,

Development of a panorama coded-aperture gamma camera for radiation detection

. Radiation Measurements. 77, 34-40 (2015). DOI: 10.1016/j.radmeas.2015.04.014
Baidu ScholarGoogle Scholar
[13] V. Popov, S. Majewski, A. G. Weisenberger,

Readout Electronics for Multi-anode Photomultiplier Tubes With Pad Matrix Anode Layout

. IEEE Nuclear Science Symposium Conference Record. 3, 2156-2159 (2003). DOI: 10.1109/NSSMIC.2003.1352307
Baidu ScholarGoogle Scholar
[14] Salar Sajedi, Navid Zeraatkar, Vahideh Moji et al.,

Design and development of a high resolution animal SPECT scanner dedicated for rat and mouse imaging

. Nucl. Instrum. Methods A. 741, 169-176 (2014). DOI: 10.1016/j.nima.2014.01.001
Baidu ScholarGoogle Scholar
[15] Valentino Orsolini Cencelli, Francesco de Notaristefani, Enrico D’Abramo,

High-speed readout for the H8500 flat panel PSPMT

. Nucl. Instrum. Methods A. 571,389-391 (2007). DOI: 10.1016/j.nima.2006.10.116
Baidu ScholarGoogle Scholar
[16] R.A. Montgomery, E.N. Cowie, M. Hoek et al.,

Multianode photomultiplier tube studies for imaging applications

. Nucl. Instrum. Methods A. 695, 326-329 (2012). DOI: 10.1016/j.nima.2011.11.026
Baidu ScholarGoogle Scholar
[17] Stan Majewski, Vladimir Popov, Randolph Wojcik et al.,

Optimization of a mini-gamma camera based on a 2×2 array of Hamamatsu H8500 PSPMTs

. Nucl. Instrum. Methods A. 569, 215-219 (2006). DOI: 10.1016/j.nima.2006.08.123
Baidu ScholarGoogle Scholar
[18] P.L. Wang, D.W. Li, B.T. Feng et al.,

Multi-channel Digitized Time-to-Digital Converter of Position Emission Tomography System

. Atomic Energy Science and Technology. 45, 637-640 (2011). DOI: 1000-6931(2011)05-0637-04.(In Chinese)
Baidu ScholarGoogle Scholar
[19] S.B. Liu, C.Q. Feng, L.F. Kang, et al.,

The non-gated charge-to-time converter for TOF detector in BES III

. Nucl. Instrum. Methods A. 621, 513-518 (2010). DOI: 10.1016/j.nima.2010.06.199
Baidu ScholarGoogle Scholar
[20] Z. Deng, Allan K. Lan, X.S. Sun et al.,

Development of an Eight-Channel Time-Based Readout ASIC for PET Applications

. IEEE Trans. Nucl. Sci. 58, 3212-3218 (2011). DOI: 10.1109/TNS.2011.2165557
Baidu ScholarGoogle Scholar
[21] P. Olcott, C. S. Levin,

Pulse Width Modulation: a Novel Readout Scheme for High Energy Photon Detection

. Nuclear Science Symposium Conference Record. 4530-4535 (2008). DOI: 10.1109/NSSMIC.2008.4774297
Baidu ScholarGoogle Scholar
[22] Stefan Siegel, Robert W. Silverman, Y.P. Shao et al.,

Simple Charge Division Readouts for Imaging Scintillator Arrays using a Multi-Channel PMT

. IEEE Trans. Nucl. Sci. 43, 1634-1641 (1996). DOI: 10.1109/23.507162
Baidu ScholarGoogle Scholar