Effect of 188Re on chromosome aberration in human peripheral blood lymphocytes

Effect of ¹⁸⁸Re on chromosome aberration in human peripheral blood lymphocytes

DONG Mo，

LI Hui-Yuan，

TAN Ming-Guang，

WU Yuan-Fang，

SHAO Song-Sheng，

LIN Ya-Ping，

ZOU Mei-Jun，

LIU Hong-Zhen

Nuclear Science and Techniques

Vol.11, No.4

pp.272-275

Published in print 01 Nov 2000

CLC：Q691.5, Q343.2+45, R730.55

27400

Human peripheral blood exposed with $^{188} Re O_{4}^{-}$ at various radioactivities for 54h was examined to observe the chromosome and chromatin aberrations at metaphases in the mitosis of lymphocytes. The findings indicate that there is an increasing tendency of the aberration yields of both types with increasing $^{188} Re O_{4}^{-}$ concentration and a dose dependency could be obtained. The aberration yield was best fitted by a quadratic model. Chromatin aberrations, aberration cells and chromosome fragments were fitted into a linear-regression model.

Peripheral bloodChromosome aberration188ReO4− irradiation-response

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