Columbia University microbeam: development of an experimental system for targeting cells individually with counted particles

WU Lijun，

HEI Tom K.，

RANDER-PEHRSON Gerhard，

WANG Shaohu，

YU Zengliang

Nuclear Science and Techniques

Vol.10, No.3

pp.143-148

Published in print 01 Aug 1999

24101

Columbia University microbeam was constructed in 1993 and finished by the end of 1995. It is well established and used routinely to irradiate cells in a highly localized spatial region with a defined number of a-particles. By using this probe, it is possible to study a number of radiobiological questions in ways that cannot be simulated by using conventional broad-field exposures. This report describes the development and current capabilities of the Columbia University microbeam, as well as the preliminary researches undertaken.

Single particleMicrobeamIrradiationRadiobiological effects

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