Accumulation contents and concentration factors (CF) for ⁵⁴Mn, ⁶⁰Co, ⁵⁸Co, ¹²⁴Sb occurring simultaneously in aquatic organisms were determined. The results show that CF correlates to nuclides, the species of organisms, the culture time and the specific activity (SA) of nuclides in water, and their relationship can be expressed by regression equations. Among shrimp, snail, ophiocephalus argus and carassius auratus, the shrimp has the highest CF particularly for ⁵⁴Mn, the CF reaches 291.5, the ophiocephalus argus has the lowest. The distribution of nuclides in fish has the magnitude order: gill>viscera>epidermis>bone>flesh.