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Sustained mutagenic effect in bone marrow cells induced by signal nuclide 134Cs retention in skeleton

Sustained mutagenic effect in bone marrow cells induced by signal nuclide 134Cs retention in skeleton

Zhu Shou-Peng
Xia Fen
Yang Wei-Dong
Nuclear Science and TechniquesVol.8, No.1pp.56-58Published in print 01 Feb 1997
20000

The skeleton transference and the retention dynamics of i.v, 134Cs are investigated. Results indicate that the retention percentage of 134Cs in skeleton could be characterized by R(t) = 0.0029exp(-0.121t) with T1/2= 5.73 d; the chromosome aberration percentage of somatic bone marrow cells increases obviously, the relationship between injected dose (X in kBq/g) and the chromosome aberration percentage can be expressed as Y = 0.0561X0.427. It should be noted that sustained elevation of chromosomal aberration rates induced by 134Cs can be upto the 47 th d.

Mutagenic effectBone marrow cellsRetention134CsSkeletonMice
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