Calculation of response of Chinese hamster cells to ions based on track structure theory

Liu Xiao-Wei，

Zhang Chun-Xiang

Nuclear Science and Techniques

pp.243-245

Published in print 01 Nov 1997

38100

Considering biological cells as single target two-hit detectors, an analytic formula to calculate the response of cells to ions is developed based on track structure theory. In the calculation, the splitting deposition energy between ion kill mode and γ kill mode is not used. The results of calculation are in agreement with the experimental data for response of Chinese hamster cells, whose response to γ rays can be described by the response function of single target two hit detector to ions.

Chinese hamster cellsTrack theoryIonsDose response

References

Butts J J, Katz R. Radiation Research, 1967; 30: 855

Katz R, Sharma S C, Homayoonfar M.

The structure of particle tracks

. In: Attix F H, ed. Radiation dosimetry, Supplement 1. New York: Academic Press, 1972; 317-383

Baidu Scholar

Google Scholar

Zhang Chun-Xiang, Dunn D E, Katz R. Radiat Prot Dosim, 1985; 13: 215

Liu Xiao-Wei, Li Mian-Feng, Yu K N. Physics in Medicine and Biology, 1994; 39: 1757

Liu Xiao-Wei, Li Miang-Feng, Luo Da-Ling et al. Int J Radiat Biol, 1996; 70(2): 227

Skarsgard L D, Kihlman B A, Parker I et al. Radiat Res Suppl, 1967; 7: 208

Katz R, Ackerson B, Homayoonfar M et al. Radiat Res, 1971; 47: 402