STUDY ON THE ACCUMULATION OF ENRICHED URANIUM UO2F2 IN SUBCELLULAR LEVEL BY ELECTRON MICROSCOPIC AUTORADIOGRAPHY

STUDY ON THE ACCUMULATION OF ENRICHED URANIUM UO₂F₂ IN SUBCELLULAR LEVEL BY ELECTRON MICROSCOPIC AUTORADIOGRAPHY

Zhu Shoupeng，

Wang Yuanchang

Nuclear Science and Techniques

pp.35-41

Published in print 01 Feb 1991

21100

In this paper we try to study the retentive peculiarity of soluble enriched uranium UO₂F₂ in subcellular level by electron microscopic autoradiography. The early dynamic accumulation of radioactivity in the body showed that enriched uranium UO₂F₂ was chiefly localized in kidney, especially accumulated in epicyte of kidney near- convoluted tubule. In liver cells, enriched uranium UO₂F₂ at first deposited in the nucleus and the cytoplasm, then accumulated in mitochondria selectively and lysosome as well. The electron microscopic autoradiographic study showed that the dynamic retention of radioactivity of enriched uranium UO₂F₂ in skeleton rose steadily throughout the exposure. Enriched uranium UO₂F₂ chiefly deposited in nucleus and mitochondria of the osteoblast as well as osteoclast.

Electron microscopic autoradiographyEnriched uranium UltrastructureNuclear emulsionAccumulation

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