THE SYNTHESES OF 1,1,1-TRIFLUORO-2- SUBSTITUTED- PHENYL-2-PROPYL-3-14C P- TOLUENESULFONATES

THE SYNTHESES OF 1,1,1-TRIFLUORO-2- SUBSTITUTED- PHENYL-2-PROPYL-3-¹⁴C P- TOLUENESULFONATES

Guo Zili，

Arthur Fry

Nuclear Science and Techniques

pp.239-242

Published in print 01 Nov 1990

39800

1,1,1,- Trifluoro- 2- substituted- phenyl- 2- propanols- 3- ¹⁴C were prepared from addition of methyl- ¹⁴C magnesium iodide to appropriate trifluoroacetophenone. These alcohols were converted into tosylates by reaction with n - butyllithium and then with p- toluenesulfonyl chloride. The yield, boiling point or melting point and pertinent spectral data of these compounds are reported.

1,1,1- Trifluoro- 2- substituted- phenyl- 2- propanols- 3- 14C1,1,1- Trifluoro- 2- substituted- phenyl- 2- propyl - 3- 14C p- toluenesulfonatesTrifluoroacetophenones14C- Labelled compound

REFERENCES

[1]

A.D. Allen et al., J. Am. Chem. Soc., 104 (1982), 207.

[2]

K.T. Liu et al., J. Am. Chem. Soc., 104 (1982), 211.

[3]

E.D. Bergman et al., Israel J. Chem., 1 (1963), 129.

[4]

P. Tarrant and R.E. Taylor, J. Org. Chem., 24 (1959), 238.