High-resolution SPECT for small-animal imaging

ADVANCED NUCLEAR INSTRUMENTATION AND DETECTION

High-resolution SPECT for small-animal imaging

QI Yu-Jin

Nuclear Science and Techniques

Vol.17, No.3

pp.164-169

Published in print 20 Jun 2006

DOI：10.1016/S1001-8042(06)60032-8

CLC：R817.4,TB811+.2

32700

This article presents a brief overview of the development of high-resolution SPECT for small-animal imaging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pinhole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection efficiency.

Small-animal SPECTMolecular imagingPinhole collimationGamma camera

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