Pre-exposure effect of low-dose 16O8+ or γ-rays on testicular endocrine of mice

Pre-exposure effect of low-dose ¹⁶O⁸⁺ or γ-rays on testicular endocrine of mice

Zhang Hong，

Wei Zeng-Quan，

Li Wen-Jian，

Chen Wei-Qiang，

Liang Jian-Ping，

Han Guang-Wu，

Huang Tao，

Li Qiang，

Dang Bing-Rong，

Xie Hong-Mei，

He Jing，

Zheng Rong-Liang，

Gao Qing-Xiang

Nuclear Science and Techniques

Vol.9, No.1

pp.47-48

Published in print 01 Feb 1998

34700

The testes of the B6C3F1 hybrid strain mice were irradiated with 0.05 Gy of ¹⁶O⁸⁺ ion/⁶⁰Co γ-ray as the pre-exposure dose, and were then irradiated with 2 Gy of ¹⁶O⁸⁺ ion/⁶⁰Co γ-ray as challenging irradiation dose at 4h after pre-exposure. The results show that irradiation of mouse testes with 2 Gy of ¹⁶O⁸⁺ ion or ⁶⁰Co γ-ray significantly diminished mouse body mass, testis mass and serum testosterone. However, pre-exposure with a low-dose (0.05 Gy) significantly reduces this kind of effect. The relative biological effectiveness of ¹⁶O⁸⁺ ion was calculated with respect to ⁶⁰Co γ-ray for the induction of reduction in body mass, testis mass and serum testosterone to be 1.71, 1.81 and 1.42, respectively.

16O8+ionPre-exposure with low-doseEndocrine capacityMouse testesAdaptive response

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