Doses of enriched uranium in testes inducing dominant lethality and skeletal abnormalities in offsprings are estimated. When intratesticular injection dose is 0.4~60µg enriched uranium; from intake to insemination, testes could receive 9.14×10^-5 ~ 1.38 × 10^-2 Gy radiation dose. Experimental results show that with the increase in the absorption dose, the number of living fetuses in a litter decreases, dominant lethality and skeletal abnormalities rise. It should be noted that relationship between the injected dose(I in µg) and the incidence of dominant skeletal abnormalities (S in %)in the offsprings can be represented by equation: S = 28.84 + 0.84 I.