3H-LABELLING OF BELLADONNA ALKALOIDS BY CATALYSED EXCHANGE WITH MICROWAVE EXCITATION

³H-LABELLING OF BELLADONNA ALKALOIDS BY CATALYSED EXCHANGE WITH MICROWAVE EXCITATION

Zhang Liming，

Zheng Dongzhu，

Yuan Jianmin，

Jiang Xiaoma，

Zhao Xialing

Nuclear Science and Techniques

Vol.3, No.3

pp.171-174

Published in print 01 Aug 1992

45400

The ³H-labelled belladonna alkaloids obtained by catalysed exchange method with microwave excitation was investigated. The specific activities of the labelled products were 16—32 TBq/mol. More than 90% labelled positions of these ³H-tracers were on phenyl rings. The radiochemical purity and chemical purity of crude products were both in 75—80%.

3H-NMRMicrowave catalysed exchange3H-anisodamine hydrobromide3H-anisodine hydrobromide3H-Atropine sulfate3H-scopolamine hydrobromide3H-labelling

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