Scanning transmission proton microscopy tomography of reconstruction cells from simulated data

LOW ENERGY ACCELERATORS AND RADIATION APPLICATIONS

Scanning transmission proton microscopy tomography of reconstruction cells from simulated data

ZHANG Conghua，

LI Min，

HOU Qing

Nuclear Science and Techniques

Vol.22, No.2

pp.89-94

Published in print 20 Apr 2011

DOI：10.13538/j.1001-8042/nst.22.89-94

30000

For scanning transmission proton microscopy tomography, to compare cell images of the proton stopping power and relative electron density, two cell phantoms are designed and simulated by code FLUKA. The cell images are reconstructed by the filtered back projection algorithm, and compared with their tomography imaging. The images of stopping power and relative electron density slightly vary with proton energies, but the internal images are of clear with high resolution. The organic glass image of relative electron density reveals the resolution power of proton tomography. Also, the simulation results reflect effects of the boundary enhancement, the weak artifacts, and the internal structure border extension by multiple scattering. So using proton tomography to analyze internal structure of a cell is a superior.

Monte Carlo simulationProton tomographyCell imageImage quality

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