A new multi-parallel-beam collimators with improved sensitivity for SPECT

RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE

A new multi-parallel-beam collimators with improved sensitivity for SPECT

MA Jiayi，

ZHAO Jingwu，

SHI Xiaodong，

ZHANG Kevin，

HUANG Runshen

Nuclear Science and Techniques

Vol.23, No.2

pp.90-96

Published in print 20 Apr 2012

DOI：10.13538/j.1001-8042/nst.23.90-96

47200

In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam collimator. The sensitivity of the single photon emission computed tomography (SPECT) system is improved by allowing projection overlapping. Comparative simulation studies were performed in the MPB collimators, general purpose parallel-beam (GPPB) collimators and high sensitivity parallel-beam (HSPB) collimators. In the simulation, attenuation, scattering and the impact of detector response were neglected. Simulation results show that the sensitivity is improved for the MPB collimator comparing with parallel-beam collimator. The behavior of spatial resolution is only different near the front face of the collimators and approaches that of the GPPB with increasing depth. Proper pre-filtering is helpful for the image reconstruction in the MPB collimators. Comparing with the HSPB collimator, the MPB can achieve a similar sensitivity and better resolution. The simulation results should be helpful to design a better collimator system of SPECT.

Multi-parallel-beamSPECTImage reconstructionSensitivity

References

[1]

Cao Z, Bal G, Accorsi R. Phys Med Biol, 2005, 50: 4609-4624.

[2]

Kamali-Asl A, Sarkar S, Shahriari M. Appl Rad Isot, 2005, 62: 461-468.

[3]

Nuyts J, Vunckx K, Defrise M. Meth, 2009, 48: 83-91.

[4]

Habraken J B A, Bruin K, Shehata M. J Nucl Med, 2001, 42: 1863-1869.

[5]

Mahmood S T, Erlandsson K, Cullum I. Phys Med Biol, 2009, 54: 3433-3449.

[6]

Mok S P, Tsui B M W, Wang Y.

Development and validation of a Monte Carlo simulation tool for multi-pinhole microSPECT

, IEEE Nucl Sci Symp Conf, 2004, 3440-3444.

Baidu Scholar

Google Scholar

[7]

Schramm N U, Ebel G, Engeland G E U. IEEE Tans Nucl Sci, 2003, 50: 315-320.

[8]

Hugg J W, Uribe J, Jansen F P. J Nucl Med, 2006, 47: 231-232.

[9]

Qian J, Bradley E L, Majewski S.

A Multi-function compact small-animal imaging system incorporating multi-pinhole standard and helical SPECT and parallel-hole SPECT

, IEEE Nucl Sci Symp Conf, 2006, 2430-2438.

Baidu Scholar

Google Scholar

[10]

Groch M W, Erwin W D. J Nucl Med Technol, 2000, 28: 233-244.

[11]

Jansena F P, Vanderheydenb J. Nucl Med Biol, 2007, 34: 733-735.

[12]

Wang Y, Tsui B M W, Baird W H. Investigation of acquisition and image reconstruction parameters for rotating multi-segment slant-hole SPECT, 2001, 2143-2146.

[13]

Xu J, Liu C, Wang Y. IEEE Trans Med Imag, 2007, 26: 906-916.

[14]

Bal G, Clackdoyle R, Kadrmas D J.

Evaluating rotating slant-hole SPECT with respect to parallel hole SPECT

, IEEE Nucl Sci Symp Conf, 2000, 3: 22-67.

Baidu Scholar

Google Scholar

[15]

Hwang D, Zeng G L. Phy Med Biol, 2005, 51: 237-252.

[16]

Hudson H, Larkin R. IEEE Trans Med Imag, 1994, 13: 601-609.

[17]

Loudos G K. Comp Med Imag Graph, 2008, 32: 83-94.

[18]

Li J, Koral K F.

Nature of ringing artifacts in SPECT reconstruction and their reduction by the use of side information Biomedical Imaging: From Nano to Macro, ISBI 2007

. The 4th IEEE international symposium, 2007, 181-184.

Baidu Scholar

Google Scholar

[19]

Zhang B.

SPECT iterative reconstruction with various types of measurements, PhD Thesis

. The University of Utah, 2007.

Baidu Scholar

Google Scholar

[20]

Peter J, Jaszczak R J, Hutton B F. IEEE Trans Nucl Sci, 2001, 49: 16-23.

[21]

Cao Z, Bal G, Accorsi R. Phys Med Biol, 2005, 50: 4609-4624.

[22]

McElroy D P, MacDonald L R, Beekman F J. IEEE Trans Nucl Sci, 2002, 49: 2139-2147.