A NEW BATO COMPLEX 99mTcCl(4-MCDO)3MeB FOR MYOCARDIAL IMAGING

A NEW BATO COMPLEX ^99mTcCl(4-MCDO)₃MeB FOR MYOCARDIAL IMAGING

Li Hongfeng，

Liu Jing，

Chen Huawei，

Liu Boli

Nuclear Science and Techniques

Vol.6, No.2

pp.117-120

Published in print 01 May 1995

20700

A new neutral complex, ^99mTcCl(4-MCDO)₃MeB,((Bis[4-methyl-1,2-cyclohex-anedionedioximato (1-)-O]-[4-methyl-1, 2-cyclohexanedione-dioximato(2-)-O]methyl-borato(2-)-N, N', N", N"', N"")-chlorotechnetium, generally called BATO (Boronic acid adducts of technetium dioximes), has been synthesized and evaluated for potential use in myocardial perfusion imaging. It has intrinsic affinity for the blood clearance. The uptake of heart, lung and blood in mice at 2min separately are 1.12, 2.48 and 6.66%ID. The complex formation is rapid, simple and highly yielded (≥ 93%). This process is easy to kit formation.

BATO complexMyocardial imaging agentHeart uptakeLabeling yield

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