RADIOIODINATION AND PHARMACOKINETICS OF BIVALENT ANALOG OF PRACTOLOL AS MYOCARDIAL IMAGING AGENT

Cao Guoxian，

Li Weiyi，

Zhang Rongjun，

Yu Huixin

Nuclear Science and Techniques

Vol.6, No.4

pp.238-240

Published in print 01 Nov 1995

25300

Solid phase exchange radioiodination method was used to label the compound. Pharmacokinetics was studied in rats and the data were dealt with by computer. The results indicate that the compound would be a potential myocardial imaging agent.

Bivalent analog of practololRadioiodinationPharmacokineticsMyocardial imaging agent125I

References

Kizuka H, Hanson R N. Nucl Med Biol, 1986; 13: 551-555

Cao G X, Li W Y, Zhang R J. Synthesis of bivalent analog of practolol as myocardial imaging agent, (in press)

Mangner T J, Wu J L, Wieland D. M. J Ory Chem, 1982; 47, 1484-1488