CATALYTIC LABELLING AND 3H NMR ANALYSES OF SOME AROMATIC AND HETEROCYCLIC COMPOUNDS

CATALYTIC LABELLING AND ³H NMR ANALYSES OF SOME AROMATIC AND HETEROCYCLIC COMPOUNDS

Zhang Liming，

R.Jones John

Nuclear Science and Techniques

pp.184-189

Published in print 01 Aug 1991

41000

This paper described the ³H NMR determination of the positions and content of 24 tritium labeled aromatic and heterocyclic compounds prepared by catalytic tritiation derivatives, pyrrole, 1,2,4- triazole, thiazole, benzothiazole, purine and derivatives, indole, indanol, piperidine and derivative, diphenylamine, N- phenylanthranilic acid, 8- OH- quinoline, naphthol, diphenylether have been tritiated by catalytic exchange method using tritiated water and platinum catalyst (from the dioxide and sodium borohydride), and the pattern of labelling has been assigned by ³H NMR spectroscopy. The results show that this exchange process can give general labelling compounds at various time and temperatures. For 4- Br- diphenylether, Raney nickel was used instead of Pt as a catalyst.

3H NMR3H labeled heterocyclic compounds3H labeled aromatic compoundsCatalytic labelling

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