SYNTHESIS OF THE RING-AND SIDE-CHAIN-14C-LABELED 1,2-BIS-(4-MORPHOLINOMETHYL-3,5-DIOXOPIPERAZIN-1-YL) PROPANE

SYNTHESIS OF THE RING-AND SIDE-CHAIN-¹⁴C-LABELED 1,2-BIS-(4-MORPHOLINOMETHYL-3,5-DIOXOPIPERAZIN-1-YL) PROPANE

Yang Zhengxiu，

Zhang Xin

Nuclear Science and Techniques

pp.233-235

Published in print 01 Nov 1991

22100

The ring-and side-chain-¹⁴C-labeled probimane, 1,2-bis (4-morpholinomethyl-3,5-dioxopiperazin-1-yl) propane were synthesized from acetic acid-1-¹⁴C in 4 steps and from ¹⁴C-formaldehyde in 1 step respectively. The radiochemical yeild for the ring labeling was 28.1%; for the side-chain labeling was 18.5%.

Probimane1,2-bis (4-morpholinomethyl-3,5-dioxopiperazin-1-yl) propane14C-labeled

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